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Types of Research and Training Programs
Updated March 15, 2013
This list is an NIAMS-specific excerpt from the NIH list of activity codes.
Fellowship Programs ( F )
Research Career Awards ( K )
Research Programs and Centers ( P )
Research Project Grants ( R )
American Recovery and Reinvestment Act (RC)
Training Programs ( T )
Cooperative Agreements ( U )
Research-Related Programs ( S )
Supplement Programs
Loan Repayment Programs
Fellowship Programs ( F ) |
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| Note: For supplements to funded research grants to support training and career development of under-represented minorities, people from socioeconomically disadvantaged backgrounds or persons with disabilities please see Supplement Programs |
| F30 | Predoctoral MD/PhD and Other Dual Doctoral Degree Individual National Research Service Award To provide predoctoral support for individual MD/PhD and other dual doctoral degree students to extend their potential for a career in research in arthritis, muscle, bone, musculoskeletal, and/or skin diseases. U.S. citizenship or permanent resident status is required. Duration: Up to 6 years Commitment: Full-time research fellowship Provisions: See FY2012 NIH Guide Notice Institutional Allowance: See FY2012 NIH Guide Notice Applications Due: April 13, August 13, December 13 |
| F31 | Predoctoral Individual National Research Service Award To provide predoctoral support of research leading to the Ph.D. or equivalent research degree for individuals to extend their potential for a career in research in arthritis, muscle, bone, musculoskeletal, and/or skin diseases. U.S. citizenship or permanent resident status is required. Duration: Up to 5 years Commitment: Full-time research fellowship Provisions: See FY2012 NIH Guide Notice Institutional Allowance: See FY2012 NIH Guide Notice Applications Due: April 13, August 13, December 13 See active F31 funding opportunities |
| F32 | Postdoctoral Individual National Research Service Award To provide postdoctoral research training to individuals to broaden their scientific background and extend their potential for research in arthritis, muscle, bone, musculoskeletal, and/or skin diseases. Requires M.D. or Ph.D. or equivalent Duration: Up to 3 years Commitment: Full-time research fellowship Provisions: See FY2009 NIH Guide Notice Institutional Allowance: See FY2009 NIH Guide Notice Applications Due: Standard dates See active F32 funding opportunities |
| F33 | Senior Fellowship Fellowships to provide opportunities for experienced scientists to make major changes in the direction of research careers, to broaden scientific background, and to acquire new research capabilities regarding arthritis, muscle, bone, musculoskeletal, and/or skin diseases. U.S. citizenship or permanent resident status is required. Level: At least 7 years postdoctoral (this is a "sabbatical" award) Duration: Up to 2 years Commitment: Full-time research fellowship Provisions: See FY2009 NIH Guide Notice (no fringe benefits) Institutional Allowance: See FY2009 NIH Guide Notice Applications Due: Standard dates See active F33 funding opportunities |
Research Career Awards ( K ) |
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| Note: For supplements to funded research grants to support training and career development of under-represented minorities, people from socioeconomically disadvantaged backgrounds or persons with disabilities please see Supplement Programs |
| K01 | Mentored Research Scientist Development Awards To provide research scientists with an additional period of sponsored research experience as a way to gain expertise in a research area new to the applicant or in an area that would demonstrably enhance the applicant's scientific career. These awards are generally reserved for individuals interested in switching to a new research field, for individuals who have interrupted their career because of illness or pressing family care responsibilities, or for faculty at minority institutions who wish to enhance their capacity for independent research. Duration: Up to 5 years Provisions: Support is provided for salary up to $75,000 for a minimum 75% effort, fringe benefits, and other research expenses up to $20,000. Applications Due: Standard dates See active K01 funding opportunities |
| K02 | Independent Research Scientist Development Awards NIAMS no longer participates in this grant mechanism. |
| K08 | Mentored Clinical Scientist Development Investigator Awards To support clinicians who need an intensive period of mentored research experience. Duration: Up to 5 years Provisions: *Support is provided for salary up to $75,000 for a minimum 75% effort, fringe benefits, and other research expenses up to $20,000. Applications Due: Standard dates *Please see NOT-AR-07-001 See active K08 funding opportunities |
| K12 | Physician Scientist Award (Program) (PSA) For support to a newly trained clinician appointed by an institution for development of independent research skills and experience in a fundamental science within the framework of an interdisciplinary research and development program. Contact: Joan Davis Nagel, MD MPH Applications Due: 10/21/2011 Additional Information: http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-11-002.html#_Section_VII._Agency_1 |
| K18 | The Career Enhancement Award Provides either full-time or part-time support for experienced scientists who wish to broaden their scientific capabilities or to make changes in their research careers by acquiring new research skills or knowledge. Career enhancement experiences supported by this award should usually last no more than one year. See active K18 funding opportunities |
| K23 | Mentored Patient-Oriented Research Career Development Award To support supervised study and research for clinically trained professionals who have the potential to develop into productive, clinical investigators focusing on patient-oriented research. Candidates must have completed their specialty and, if applicable, subspecialty training prior to receiving an award. Duration: 3 to 5 years Provisions: *Support is provided for salary up to $75,000 for a minimum 75% effort, fringe benefits, and other research expenses up to $25,000. Applications Due: Standard dates *Please see NOT-AR-07-001 See active K23 funding opportunities |
| K24 | Midcareer Investigator Award in Patient-Oriented Research
To support protected time for clinicians to allow them time for patient-oriented research and to act as mentors for beginning clinical investigators. Candidates must have completed their specialty training within 15 years of submitting the application. Candidates must be working in a research environment, conducting patient-oriented research, and have independent research support. Duration: 3 to 5 years. Provisions: Support up to 50% of the NIH salary cap ($196,700 in FY 2009) is provided and up to $50,000 in selected research expenses. Applications Due: Standard dates See active K24 funding opportunities |
| K25 | Mentored Quantitative Research Career Development Award To support supervised study and research for investigators with quantitative scientific and engineering backgrounds outside of biology or medicine who have made a commitment to focus their research endeavors on biomedical research. This mechanism is aimed at research-oriented scientists with experience at the level of junior faculty who have the potential to integrate their expertise with biomedicine and to develop into productive investigators. Duration: 3 to 5 years. Provisions: Support is provided for salary up to $75,000 for a minimum 75% effort, fringe benefits, and other research expenses up to $25,000. Applications Due: Standard dates |
| K99/R00 | NIH Pathway to Independence (PI) Award The Pathway to Independence Award is uniquely designed to facilitate the transition of outstanding postdoctoral candidates from mentored to independent research positions. The award contains two components, a mentored (K99) phase that can last up to 2 years and an independent (R00) phase, which will have a duration of 3 years. The objective of the program is to facilitate research independence earlier in an investigator's career. Investigators complete supervised research, and apply for an independent research faculty position, during the mentored phase of the award. Activation of the independent award phase is administrative, and is contingent upon the investigator securing an independent research position. Eligible candidates will have no more than 5 years of postdoctoral research at the time of application (initial or amended). Award recipients are expected to obtain R01 support during the independent phase of the award. Provisions: For mentored candidates in an extramural institution, NIAMS will provide up to $50,000 per year for salary support (up to $75,000 per year for applicants with an M.D. degree), plus fringe, and up to $20,000 for research support costs. Budget details for mentored candidates in the NIH intramural program will be negotiated with the sponsoring laboratory and will be consistent with offers to scientists in comparable positions. See active K99/R00 funding opportunities |
| KM1 | Institutional Career Enhancement Awards - Multi-Yr Funding Provides for part time (minimum 25% effort) up to full-time support for medical, scientific, statistics and health care professionals with post-doctoral or equivalent experience selected by an institution, to broaden their research capabilities by acquiring new research skills or knowledge. Further it provides for curriculum development of new programs to support these same types of individuals. This is an institutional mentored career program, not an individual program. It is also a multi-year funded institutional mentored career development activity thus ICs need OER prior approval to use the KM1. |
Research Programs and Centers ( P ) |
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| P01 | Research Program Project Grants As of 1 April 2011, the NIAMS is no longer participating in PAR-10-266, the NIGMS P01 funding opportunity announcement. The NIAMS limits P01support to NIAMS investigators who will not have had 10 years of P01 or 2 competing segments of support as stated in NOT-AR-05-007 How to Apply: As of 25 September 2010, all NIH applications must be submitted in response to a funding opportunity announcement (FOA). The NIAMS has published its own FOA (PAR-11-188) in order to allow our eligible renewal applicants to apply. If you have questions about your eligibility, please contact the NIAMS before you plan to submit your application. Publication of the NIAMS funding opportunity announcement for P01s is solely to provide a mechanism for our eligible renewal applicants to apply; it is not intended as a solicitation for the NIAMS to accept new PPGs. Special instructions: Budgets are limited to $1 million in direct costs per year. Facilities and Administrative (F&A) Costs for subcontracts do not count as part of the direct costs. P01 applications are still submitted on the paper PHS 398 form. On Line #2, applicants must check “Yes” and PAR-11-188 should be entered for the Number of the solicitation. Applications Due: Renewal or resubmissions applications ~ May 25, September 25 You must request permission to submit your P01 application to the NIAMS. Please see Guidelines for Applications with Direct Costs of $500,000 or More in Any One Year See active P01 funding opportunities |
| P30 | Research Core Centers To promote a cooperative interaction among basic science and clinical investigators in a manner that will enrich the effectiveness of ongoing research and promote new research. Any institution or consortium with an active program of excellence in basic and clinical biomedical research in skin diseases, musculoskeletal disorders or rheumatic diseases, may qualify for support through a Core Center. A strong biomedical research base is the prerequisite for establishment of a Core Center and an important component in considering continued funding of an established center. The components of a core center include 2 or more research cores and an administrative core that includes an Enrichment Program. Duration: 5 years Budget Cap: $400,000 direct costs Core Centers for Musculoskeletal Biology and Medicine: Letters of intent due May 31, 2013; Applications Due July 1, 2013 Skin Diseases Research Core Centers: Letters of intent due August 20, 2013; Applications Due September 20, 2013 Additional Information: suggested exhibits for P30 applications - PDF format See active P30 funding opportunities |
| P50-CORT | Centers of Research Translation (CORT) Contact: Ms. Justine Buschman To promote translational research through a multidisciplinary approach on a disease specific theme. A CORT should have both basic and clinical research components. Duration: 5 years Budget Cap: $1,000,000 direct costs Applications Due: By RFA only Additional Information: CORT Guidelines - PDF format / CORT FAQs - PDF format |
| P50-ORWH | Specialized Centers of Research on Sex and Gender Factors Affecting Women’s Health (SCOR) Contact: Dr. Bernadette Tyree The Office of Research on Women's Health (ORWH) serves as a focal point for women's health research at the NIH. The ORWH promotes, stimulates, and supports efforts to improve the health of women through biomedical and behavioral research. ORWH works in partnership with the NIH Institutes as well as the Food and Drug Administration (FDA) to ensure that women's health research is part of the scientific framework at NIH and throughout the scientific community. The ORWH announces the Specialized Centers of Interdisciplinary Research on Sex and Gender Factors Affecting Women's Health (SCOR) program. These centers will provide new opportunities for interdisciplinary approaches to advancing studies on how sex and gender factors affect women's health. Each SCOR should develop an interdisciplinary research agenda bridging basic and clinical research on sex/gender factors underlying a priority women’s health issue. Duration: 5 years Budget Cap: $750,000 direct costs Applications Due: By RFA only |
| P60 | Multidisciplinary Clinical Research Centers (MCRC) Contact: Ms. Justine Buschman To support a full range of outstanding multidisciplinary clinical research in the areas of arthritis and musculoskeletal and skin diseases. Each MCRC is organized around a methodology core and must include a minimum of two highly meritorious projects. The projects and overall Center can be focused on one or more diseases/conditions. The methodology core must demonstrate that it can provide support for multidisciplinary approaches for clinical projects within and outside the MCRC. The methodology core is the foundation of the Center, providing key support for development and implementation of clinical projects. The director of the MCRC, aided by an executive committee and the methodology core, provides leadership to assure a rigorous research approach and to focus all research projects on critical issues relevant to disease prevention or to assessment and/or to improve outcomes of patients with chronic diseases/conditions within the mission of the NIAMS. The MCRCs will build on a meritorious research base and are expected to leverage existing institutional infrastructure resources. Duration: 5 years Budget Cap: $800,000 direct costs Applications Due: By RFA only Additional Information: MCRC Guidelines - PDF format WORD format |
Research Project Grants ( R ) |
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| ARRA R15 | Recovery Act Limited Competition: Academic Research Enhancement Award (R15) Additional Information: http://grants.nih.gov/recovery/ RFA-OD-09-007 |
| R01 | Research Grants Definition and other information provided under the R01 Guidelines related links. Additional Information: Modular Grants NIAMS Building Interdisciplinary Research Team (BIRT) Competitive Revision Awards (R01 only) Contact: Carl Baker and Fei Wang To promote building NEW interdisciplinary teams among independent investigators that pursue a clear and significant scientific opportunity in an area of shared interest of relevance to NIAMS. At least one investigator must have an active NIAMS-supported R01. Duration: 1 year Budget Cap: $100,000 direct costs Letters of intent due: October 15, 2012 ; June 17, 2013; June 16, 2014 Applications due: November 15, 2012 ; July 15, 2013; July 15, 2014 Additional information: BIRT FAQs – PDF Format See active R01 funding opportunities |
| R03 | Small Research Grants The NIAMS Small Grant Program for New Investigators (R03) is intended for researchers that need funding to develop preliminary data for their first R01 application. These grants support studies related to arthritis, musculoskeletal or skin diseases or disorders. Duration: No more than 3 years, not renewable. Budget Cap: $50,000/yr. direct costs. Applications Due: 03/20/2012, 07/20/2012, 11/20/2012, 03/20/2013, 07/19/2013, 11/20/2013, 03/20/2014, 07/21/2014, 11/20/2014 NIAMS also participates in other R03 program announcements for specific topics of research. See active R03 funding opportunities |
| R13/U13 | Conference and Scientific Meeting Grants Contact: Ms. Theresa Smith Definition and other information provided under the R13 / U13 Guidelines related links. See active R13/U13 funding opportunities |
| R15 | AREA Grants Definition and other information provided under the R15 Guidelines related links. See active R15 funding opportunities |
| R21 | NIAMS High Innovation Exploratory/Developmental Research Grant Program NIAMS accepts applications in response to PA-10-069 "NIH Exploratory/Developmental Research Grant Program (Parent R21)" proposing studies related to arthritis, musculoskeletal or skin diseases or disorders. Potential applicants are strongly encouraged to discuss the suitability of the project for this program announcement with the NIAMS Program Director for that research topic area. See NOT-AR-10-023 for additional information regarding NIAMS support for innovative research using R21 grants. In making funding decisions on R21 applications, NIAMS will place a higher priority on projects that are:
Contact: See NIAMS supported scientific areas and contact information for the Program Directors. Duration: 2 years Budget Cap: $275,000 direct costs spread over two years Applications Due: Standard dates Projects of limited time and scope that do not meet these characteristics of innovative, ground-breaking research should consider applying for a small Research Project Grant (Parent R01). For example, an R01 for two or three years at $100,000 direct cost per year could support a pilot project. New investigators are encouraged to apply for an R01 (see NOT-OD-09-013, "Revised New and Early Stage Investigator Policies) or an R03 (see NIAMS Small Grant Program for New Investigators). Preference in funding decisions for R21 grants will be given to projects within the NIAMS mission areas that are especially innovative, ground-breaking and have a high potential impact on these fields. NIAMS also has funding opportunities for R21 grants on specific topics. The goal of supporting innovative, ground-breaking, highly significant research with the R21 activity code also applies to these funding opportunities. See active R21 funding opportunities |
| R25 | Education Projects For support to develop and/or implement a program as it relates to a category in one or more of the areas of education, information, training, technical assistance, coordination, or evaluation. In this case, the Clinical Research Education and Career Development (CRECD) grant awards support development and implementation of curriculum-dependent programs in minority institutions to train selected doctoral and postdoctoral candidates in clinical research leading to a Master of Science in Clinical Research or Master of Public Health in a clinically relevant area. A successful program will result in an accredited master's degree program to produce trained and independent clinical researchers who can become engaged in conducting translational and/or patient-oriented research projects. Duration: Up to 5 years to a minority institution Budget Cap: $500,000/yr direct costs Applications Due: By RFA only |
| R34 | Clinical Trial Planning Grants Definition and other information provided under the R34 Guidelines related links. Applications Due: Standard dates |
| R41/R42 | Small Business Technology Transfer (STTR) Program The STTR program is a set aside program designed to support innovative research that has the potential for commercialization of the subject research conducted cooperatively by a small business concern and research institution. Innovation and the potential for commercialization are two of the review criteria considered in the scientific and technical merit evaluation process. At least 40 percent of the research project is to be conducted by the small business concern and at least 30 percent of the work is to be conducted by the single, “partnering” research institution. Phase I (R41) is normally provided for one year/$100,000, which includes direct cost, facilities and administrative cost, and fixed fee. The facilities and administrative cost maximum is 40%, if no current negotiated rate. Fixed Fee is 7% maximum of direct cost and facilities and administrative cost for grantee institution only. Phase II (R42) is normally two years/$750,000, which includes direct cost, facilities and administrative cost, and fixed fee. The facilities and administrative cost maximum is 25% or current negotiated rate. The applicant may negotiate with NIH. Fixed Fee is 7% maximum of direct cost and facilities and administrative cost for grantee institution only. However, applicants may propose longer periods of time and greater amounts of funds necessary for completion of the project, prior discussion and justification with Program Official is required. Contact: Xibin Wang wangx1@mail.nih.gov Applications Due: April 5, August 5, December 5 Additional Information: Office of Extramural Research: Small Business Innovation Research (SBIR) and Small Business Technology (STTR) Programs See active R41/R42 funding opportunities |
| R43/R44 | Small Business Innovation Research (SBIR) Program To support small businesses in any biomedical or behavioral research area as described in the yearly solicitation. Phase I (R43) is normally provided for six months/$100,000, which includes direct cost, facilities and administrative cost and fixed fee. The facilities and administrative cost maximum is 40%, if no current negotiated rate. Fixed Fee is 7% maximum of direct cost and facilities and administrative cost for grantee institution only. Phase II (R44) is normally two years/$750,000, which includes direct cost, facilities and administrative cost and fixed fee. The facilities and administrative cost maximum is 25% or current negotiated rate. The applicant may negotiate with NIH. Fixed Fee is 7% maximum of direct cost and facilities and administrative cost for grantee institution only. However, applicants may propose longer periods of time and greater amounts of funds necessary for completion of the project. Contact: Xibin Wang wangx1@mail.nih.gov Applications Due: April 5, August 5, December 5 Additional Information: Office of Extramural Research: Small Business Innovation Research (SBIR) and Small Business Technology (STTR) Programs See active R43/R44 funding opportunities |
| RC4 | High Impact Research and Research Infrastructure Programs—Multi-Yr Funding To support multi-year funded research with high impact ideas that may lay the foundation for new fields of investigation; accelerate breakthroughs; stimulate early and applied research on cutting-edge technologies; foster new approaches to improve the interactions among multi- and interdisciplinary research teams; or, advance the research enterprise in a way that could stimulate future growth and investments and advance public health and health care delivery. This activity code could support either a specific research question or propose the creation of a unique infrastructure/resource designed to accelerate scientific progress in the future. It is the multi-year funded companion activity code to the existing RC2; thus ICs need OER prior approval to use the RC4. |
Training Programs ( T ) |
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| T32 | Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants NIAMS offers these grants to enable institutions to make NRSAs for predoctoral and postdoctoral research training to individuals selected by them in the fields of arthritis, muscle, bone, musculoskeletal, and/or skin diseases. Duration: 5-year institutional grant (renewable). Applications Due: May 25 Additional Information: NIAMS T32 Program See active T32 funding opportunities |
Cooperative Agreements ( U ) |
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| U01 | Research Project Cooperative Agreements These are agreements between NIH and the award recipient in which the NIH acts as the partner in the research effort for projects similar to grants. See active U01 funding opportunities |
| U19 | Research Program--Cooperative Agreements To support a research program of multiple projects directed toward a specific major objective, basic theme or program goal, requiring a broadly based, multidisciplinary and often long-term approach. A cooperative agreement research program generally involves the organized efforts of large groups, members of which are conducting research projects designed to elucidate the various aspects of a specific objective. Substantial Federal programmatic staff involvement is intended to assist investigators during performance of the research activities, as defined in the terms and conditions of award. The investigators have primary authorities and responsibilities to define research objectives and approaches, and to plan, conduct, analyze, and publish results, interpretations and conclusions of their studies. Each research project is usually under the leadership of an established investigator in an area representing his/her special interest and competencies. Each project supported through this mechanism should contribute to or be directly related to the common theme of the total research effort. The award can provide support for certain basic shared resources, including clinical components, which facilitate the total research effort. These scientifically meritorious projects should demonstrate an essential element of unity and interdependence. |
| U34 | Clinical Planning Grant Cooperative Agreement This cooperative agreement would provide support, substantial Federal programmatic involvement, and technical assistance for the initial development of a clinical trial. Also, it would include the establishment of the research team; the development of tools for data management and oversight of the research; the development of a trial design and other essential elements of the study, such as the protocol, recruitment strategies, and procedure manuals; and to collect feasibility data. See active U34 funding opportunities |
| U54 | Specialized Center Cooperative Agreements These agreements support research and development from basic to clinical, including ancillary supportive activities that create a multidisciplinary focus on a disease or biomedical problem. The centers may also serve as regional or national resources for special research purposes. |
| UH2/UH3 | Exploratory/Developmental Cooperative Agreement To support the development of new research activities in categorical program areas. (Support generally is restricted in level of support and in time.) The UH3 award is to provide a second phase for the support for innovative exploratory and development research activities initiated under the UH2 mechanism. Although only UH2 awardees are generally eligible to apply for UH3 support, specific program initiatives may establish eligibility criteria under which applications could be accepted from applicants demonstrating progress equivalent to that expected under UH2. |
| UL1 | Cooperative Agreements In these agreements, the award recipient retains the primary responsibility and dominant role for planning, directing, and executing the proposed project, with NIH staff being substantially involved as a partner with the awardee. |
| UM1 | Multi-Component Research Project Cooperative Agreements To support large-scale cooperative agreements involving complex clinical trials with multiple components, e.g. clinical networks. The components represent a variety of supporting functions and are not independent of the research projects. Substantial Federal programmatic staff involvement is intended to assist investigators during performance of the research activities, as defined in the terms and conditions of award. The performance period may extend up to seven years but only through the established deviation request process. ICs desiring to use this activity code for programs greater than 5 years must receive OPERA prior approval through the deviation request process. See active UM1 funding opportunities |
Research-Related Programs ( S ) |
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| S10 | Biomedical Research Support Shared Instrumentation Grants (NCRR) To make available to institutions with a high concentration of NIH extramural research awards, research instruments which will be used on a shared basis. |
| Si2 | Intramural Clinical Scholar Research Award This program will encourage exceptionally talented clinical researchers to conduct research in the Intramural Research Program for a specified period of time who will then be able to work with an extramural institution to develop an independent research grant application for follow-on support. This code can only be used as phase 1 (intramural) of a 2-phase intramural/extramural program. No extramural award can be issued using this activity code. NIH Intramural and OPERA prior approval is required to use this activity code. Applications Due: June 24, 2013 Lasker Clinical Research Scholars Program (Si2) RFA-OD-13-004 See active Si2 funding opportunities |
Supplement Programs |
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| Note: Supplemental applications accepted year round except from July 1 through October 1 |
| Administrative Supplements The National Institutes of Health (NIH) has recently posted guidance regarding administrative supplements. The announcement informs principal investigators (PIs) holding specific types of NIH research grants that funds may be available for administrative supplements. The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) allows three primary types of administrative supplements:
To award new funds for a significant expansion of a project’s scope a grantee must apply for a competing revision and undergo peer review. Before proceeding with any supplement request, PIs are advised to contact their program officer to discuss scientific need and their grants management specialist to discuss budget and policy issues. |
Loan Repayment Programs |
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| LRP Loan Repayment Programs Contact: Laura K. Moen, Ph.D. LRP Information Center: 866-849-4047 or lrp@nih.gov The NIAMS welcomes applications to the NIH Loan Repayment Program. We are interested in applications that meet the eligibility requirements for either the Clinical Research Program or the Pediatric Research Program. We are particularly interested in applications from physician-scientists. Please visit http://www.lrp.nih.gov for eligibility information, application instructions and more. |



